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A palladium-catalyzed cross-electrophile coupling reaction involving sulfur dioxide for the direct synthesis of diversely functionalized sulfones

Baojian Xiong, Jinyu Zhang, Ting Wang, Xuemei Zhang, Gui‐Juan Cheng, Zhong Lian

2023Organic Chemistry Frontiers20 citationsDOI

Abstract

A palladium catalyzed multi-component cross-electrophile coupling involving sulfur dioxide is presented here. This protocol features mild reaction conditions, wide substrate scope, good functional group tolerance and excellent regioselectivity.

Topics & Concepts

ChemistryElectrophilePalladiumRegioselectivityCatalysisFunctional groupSubstrate (aquarium)Sulfur dioxideCoupling reactionCoupling (piping)Combinatorial chemistryOrganic chemistryGeologyEngineeringMechanical engineeringPolymerOceanographySulfur-Based Synthesis TechniquesCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods
A palladium-catalyzed cross-electrophile coupling reaction involving sulfur dioxide for the direct synthesis of diversely functionalized sulfones | Litcius