ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
Kathryn R. Bowles, M. Catarina Silva, Kristen Whitney, Taylor Bertucci, Joshua Berlind, Jesse D. Lai, Jacob C. Garza, Nathan C. Boles, Sidhartha Mahali, Kevin H. Strang, Jacob Marsh, Cynthia Chen, Derian A. Pugh, Yiyuan Liu, Ronald E. Gordon, Susan K. Goderie, Rebecca Chowdhury, Steven Lotz, Keith Lane, John F. Crary, Stephen J. Haggarty, Celeste M. Karch, Justin K. Ichida, Alison Goate, Sally Temple
Topics & Concepts
BiologyRNA splicingGlutamatergicOrganoidMutationGeneticsNeuroscienceAlternative splicingExonGeneGlutamate receptorRNAReceptorRNA regulation and diseaseRNA Research and SplicingPluripotent Stem Cells Research