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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids

Kathryn R. Bowles, M. Catarina Silva, Kristen Whitney, Taylor Bertucci, Joshua Berlind, Jesse D. Lai, Jacob C. Garza, Nathan C. Boles, Sidhartha Mahali, Kevin H. Strang, Jacob Marsh, Cynthia Chen, Derian A. Pugh, Yiyuan Liu, Ronald E. Gordon, Susan K. Goderie, Rebecca Chowdhury, Steven Lotz, Keith Lane, John F. Crary, Stephen J. Haggarty, Celeste M. Karch, Justin K. Ichida, Alison Goate, Sally Temple

2021Cell163 citationsDOIOpen Access PDF

Topics & Concepts

BiologyRNA splicingGlutamatergicOrganoidMutationGeneticsNeuroscienceAlternative splicingExonGeneGlutamate receptorRNAReceptorRNA regulation and diseaseRNA Research and SplicingPluripotent Stem Cells Research
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids | Litcius