Litcius/Paper detail

New bis([1,2,4]triazolo)[4,3-a:3′,4′-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation

Mohammed M. Alanazi, Hazem A. Mahdy, Nawaf A. Alsaif, Ahmad J. Obaidullah, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Sultan M. Alsubaie, Mohammed A. Dahab, Ibrahim H. Eissa

2021Bioorganic Chemistry96 citationsDOI

Topics & Concepts

ChemistryIn silicoSorafenibApoptosisQuinoxalineCytotoxic T cellDocking (animal)Cell cultureCytotoxicityCell cycleCaspase 3IC50StereochemistryLead compoundCell growthIn vitroBiochemistryProgrammed cell deathCancer researchBiologyNursingGeneticsHepatocellular carcinomaGeneOrganic chemistryMedicineSynthesis and Biological EvaluationSynthesis and biological activityQuinazolinone synthesis and applications