Tertiary amine modification enables triterpene nanoparticles to target the mitochondria and treat glioblastoma via pyroptosis induction
Xingchun Gao, Xiangjun Tang, Zewei Tu, Jiang Yu, Youmei Bao, Gretchen Long, Wendy C. Sheu, Haoan Wu, Jia Liu, Jiangbing Zhou
Topics & Concepts
TriterpeneMaterials scienceAmine gas treatingPyroptosisGlioblastomaMitochondrionNanotechnologyNanoparticleSurface modificationCombinatorial chemistryBiochemistryOrganic chemistryApoptosisCancer researchChemistryMedicineProgrammed cell deathPathologyPhysical chemistryAlternative medicineInflammasome and immune disordersATP Synthase and ATPases ResearchCurcumin's Biomedical Applications