New thiazolopyrimidine as anticancer agents: Synthesis, biological evaluation, DNA binding, molecular modeling and ADMET study
Sara T. Al‐Rashood, Shymaa S. Elshahawy, Asmaa M. El-Qaias, Dina S. El-Behedy, Alshaimaa A. Hassanin, Selwan M. El‐Sayed, Shahenda M. El‐Messery, Moataz A. Shaldam, Ghada S. Hassan
Topics & Concepts
ChemistryDNAMolecular modelStereochemistryCombinatorial chemistryDoxorubicinBiological activityBinding siteHydrogen bondDocking (animal)PurineIn vitroMoleculeBiochemistryEnzymeOrganic chemistryMedicineChemotherapySurgeryNursingSynthesis and biological activitySynthesis and Biological EvaluationSynthesis and Characterization of Heterocyclic Compounds