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<i>N</i>-Sulfenyl phthalimide enabled Markovnikov hydrothiolation of unactivated alkenes <i>via</i> ligand promoted cobalt catalysis

Xiang-Rui Li, Rong-Jin Zhang, Yonghong Xiao, Qing‐Xiao Tong, Jian‐Ji Zhong

2023Organic Chemistry Frontiers32 citationsDOI

Abstract

N -Sulfenyl phthalimides as efficient radicalophile reagents is herein reported to enable the Markovnikov hydrothiolation of unactivated alkenes by cobalt catalysis with exclusive regio-selectivity and wide functional group tolerance.

Topics & Concepts

Markovnikov's ruleChemistryPhthalimidesPhthalimideCobaltCatalysisCombinatorial chemistryOrganic chemistryRegioselectivitySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsChemical Synthesis and Reactions
<i>N</i>-Sulfenyl phthalimide enabled Markovnikov hydrothiolation of unactivated alkenes <i>via</i> ligand promoted cobalt catalysis | Litcius