Discovery of fingolimod based on the chemical modification of a natural product from the fungus, Isaria sinclairii
Kenji Chiba
Topics & Concepts
FingolimodNatural productIn vivoPharmacologyMechanism of actionMultiple sclerosisReceptorIn vitroChemistryBiologyMedicineImmunologyBiochemistryBiotechnologySphingolipid Metabolism and SignalingPhytochemistry and Biological ActivitiesPlant-derived Lignans Synthesis and Bioactivity