High-Yielding Water-Soluble Asymmetric Cyanine Dyes for Labeling Applications
Natalia Wolf, Louise Kersting, Christoph Herok, Cornelius Mihm, Jürgen Seibel
Abstract
A simple and efficient microwave-assisted synthesis of asymmetric pentamethine cyanine dyes with various functional groups was developed, which allows high-yielding results. The synthesized dyes are modifiable and suitable for single-molecule imaging in biological and medical sciences by application of click chemistry or classic esterification and amidation.
Topics & Concepts
CyanineClick chemistryCombinatorial chemistryChemistryMoleculeWater solubleOrganic chemistryNanotechnologyPhotochemistryMaterials scienceFluorescencePhysicsQuantum mechanicsClick Chemistry and ApplicationsPhotodynamic Therapy Research StudiesChemical Synthesis and Analysis