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Astragalin attenuates depression-like behaviors and memory deficits and promotes M2 microglia polarization by regulating IL-4R/JAK1/STAT6 signaling pathway in a murine model of perimenopausal depression

Guangda Yao, Zijun Bai, Jianguo Niu, Rui Zhang, Youyuan Lu, Tiantian Gao, Hanqing Wang

2022Psychopharmacology42 citationsDOI

Topics & Concepts

MicrogliaNeuroinflammationNitric oxide synthaseInternal medicineEndocrinologyMedicineSignal transductionChemistryNitric oxidePharmacologyCell biologyInflammationBiologyNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersMenopause: Health Impacts and Treatments
Astragalin attenuates depression-like behaviors and memory deficits and promotes M2 microglia polarization by regulating IL-4R/JAK1/STAT6 signaling pathway in a murine model of perimenopausal depression | Litcius