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BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease

Michael A. Harris, Maya El Hindy, Marcela Usmari Moraes, Fred Hudd, Mai Ahmed Shafei, Ming Dong, Mohammed Hezwani, Paul A. Clark, Michael J. House, Tom E. Forshaw, Patrick G. Kehoe, Myra E. Conway

2020Free Radical Biology and Medicine23 citationsDOIOpen Access PDF

Topics & Concepts

AutophagymTORC1Cell biologyPhosphorylationProtein kinase CBiologyNeurodegenerationMechanistic target of rapamycinProtein kinase BKinaseDownregulation and upregulationChemistryBiochemistryApoptosisDiseaseInternal medicineMedicineGeneAlzheimer's disease research and treatmentsAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease
BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease | Litcius