The disturbance of protein synthesis/degradation homeostasis is a common trait of age-related neurodegenerative disorders
Fabio Di Domenico, Chiara Lanzillotta
Topics & Concepts
ProteostasisUnfolded protein responseCell biologyEndoplasmic reticulumProteasomeProtein foldingBiologyChaperone (clinical)Protein aggregationAutophagyNeurodegenerationProtein degradationBiochemistryApoptosisDiseaseMedicinePathologyEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyAlzheimer's disease research and treatments