Hypoxia-responsive micelles deprive cofactor of stearoyl-CoA desaturase-1 and sensitize ferroptotic ovarian cancer therapy
Jiajia Luo, Yaqi Shang, Ning Zhao, Xiaoying Lü, Zheng Wang, Xin Li, Xuan Meng, Yanjun Zhao, Yanjun Zhao
Topics & Concepts
Downregulation and upregulationOvarian cancerHypoxia (environmental)Cancer researchCancer therapyCancerCofactorMedicineChemistryEnzymeBiochemistryInternal medicineOxygenGeneOrganic chemistryCancer, Lipids, and MetabolismRNA modifications and cancerFerroptosis and cancer prognosis