Mapping Robust Genetic Variants Associated with Exercise Responses
Javier Alvarez‐Romero, Sarah Voisin, Nir Eynon, Danielle Hiam
Abstract
This review summarised robust and consistent genetic variants associated with aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs and 7 SNPs that are robustly associated with variance in aerobic-related and resistance-related phenotypes respectively. To date, there is very little literature ascribed to understanding the interplay between genes and environmental factors and the development of physiological traits. We discuss future directions, including large-scale exercise studies to elucidate the functional relevance of the discovered genomic markers. This approach will allow more rigour and reproducible research in the field of exercise genomics.
Topics & Concepts
RigourPhenotypeGenetic variantsBiologySingle-nucleotide polymorphismGenomicsComputational biologyGeneticsGenome-wide association studyBioinformaticsGeneGenotypeGenomeGeometryMathematicsGenetics and Physical PerformanceAdipose Tissue and MetabolismMuscle metabolism and nutrition