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Oxidative Rearrangement Reactions Mediated by Hypervalent-Iodine Reagents

Yang Zhifang, Yifu Cheng, Zhang Beibei, Yunyi Dong, Chi Han, Yunfei Du

2022Chinese Journal of Organic Chemistry12 citationsDOIOpen Access PDF

Abstract

During the past 40 years, hypervalent-iodine chemistry has developed rapidly and extensive attention has been received from many organic researchers. For their advantages of low toxicity, easy preparation and environmental benignity, hypervalent iodine reagents have been widely applied in various types of organic transformation including oxidative coupling, functionalization, and rearrangement reactions. Among them, there exist a series of oxidative rearrangement reactions, which can be classified into many types including C to X migration (XC, N or O), X to C migration (XN, O, S, Si or I), I to X migration (XO or N) and sigmatropic rearrangement. This review comprehensively summarizes the oxidative rearrangement reactions enabled by hypervalent iodine reagents, providing convenience for organic readers to learn the progress of this research field.

Topics & Concepts

Hypervalent moleculeChemistryIodineReagentOxidative phosphorylationIodine compoundsCombinatorial chemistryOrganic chemistryBiochemistryOxidative Organic Chemistry ReactionsSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods