Rapid discovery of terpene tailoring enzymes for total biosynthesis
Yunlong Sun, Jennifer Gerke, Kevin Becker, Eric Kuhnert, Bart Verwaaijen, Daniel Wibberg, Jörn Kalinowski, Marc Stadler, Russell J. Cox
Abstract
. Compounds produced in a single step include the natural product hypoxylan A and an epimer of guignaderemophilane C. A new fungal aromatase was discovered that produces phenols by oxidative demethylation.
Topics & Concepts
TerpeneBiosynthesisEnzymeChemistryBiochemistryPlant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisEnzyme Catalysis and Immobilization