Antifungal Development and the Urgency of Minimizing the Impact of Fungal Diseases on Public Health
Haroldo César de Oliveira, Bárbara Tavares Bezerra, Márcio L. Rodrigues
Abstract
Fungal infections are a major public health problem resulting from the lack of public policies addressing these diseases, toxic and/or expensive therapeutic tools, scarce diagnostic tests, and unavailable vaccines. In this Perspective, we discuss the need for novel antifungal alternatives, highlighting new initiatives based on drug repurposing and the development of novel antifungals.
Topics & Concepts
AntifungalPublic healthDrug developmentAntifungal drugsDrug repositioningRepurposingIntensive care medicinePerspective (graphical)MedicineDrugBiologyPharmacologyComputer sciencePathologyEcologyDermatologyArtificial intelligenceAntifungal resistance and susceptibilityFungal Infections and StudiesNail Diseases and Treatments