Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response
Siyu Tan, Zehua Wang, Na Li, Xiaowei Guo, Yankun Zhang, Hongxin Ma, Xueqi Peng, Ying Zhao, Chunyang Li, Lifen Gao, Tao Li, Xiaohong Liang, Chunhong Ma
Topics & Concepts
Tumor microenvironmentMacrophage polarizationReprogrammingCancer researchTranscription factorBiologyProinflammatory cytokineImmunotherapyIRF1Cancer cellCancer immunotherapyPhenotypeImmune systemInflammationImmunologyCancerCellGeneTumor cellsGeneticsImmune cells in cancerEpigenetics and DNA MethylationPhagocytosis and Immune Regulation