Outer Membrane Vesicles of Actinobacillus pleuropneumoniae Exert Immunomodulatory Effects on Porcine Alveolar Macrophages
Zhuang Zhu, Fabio Antenucci, Hanne C. Winther‐Larsen, Kerstin Skovgaard, Anders Miki Bojesen
Abstract
Owing to their built-in adjuvanticity and antigenicity, bacterial outer membrane vesicles (OMVs) are gaining increasing attention as potential vaccines for both human and animal use. OMVs released by Actinobacillus pleuropneumoniae , an important respiratory pathogen in pigs, have also been investigated for vaccine development.
Topics & Concepts
Actinobacillus pleuropneumoniaeBacterial outer membraneMicrobiologyVesicleActinobacillusAlveolar macrophagePasteurellaceaeChemistryBiologyMacrophageMembraneBacteriaAntibioticsIn vitroBiochemistrySerotypeEscherichia coliGeneticsGeneHaemophilus influenzaeMicrobial infections and disease researchBacteriophages and microbial interactionsBacterial Infections and Vaccines