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Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases

Yan He, Yi Wang, Kun Yang, Jiao Jia, Hong Zhan, Youjun Yang, De Lv, Weihong Li, Weijun Ding

2022Molecules32 citationsDOIOpen Access PDF

Abstract

Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including olive, and is highly safe for human beings. In recent years, it has been reported that MA has anti-inflammatory, antioxidant, anti-tumor, hypoglycemic, neuroprotective and other biological activities. More and more experimental data has shown that MA has a good therapeutic effect on multiple organ diseases, indicating that it has great clinical application potential. In this paper, the extraction, purification, identification and analysis, biological activity, pharmacokinetics in vivo and molecular mechanism of MA in treating various organ diseases are reviewed. It is hoped to provide a new idea for MA to treat various organ diseases.

Topics & Concepts

TriterpenePharmacologyNeuroprotectionMechanism (biology)In vivoPharmacokineticsChemistryComputational biologyTraditional medicineMedicineBiologyBiotechnologyPathologyAlternative medicineEpistemologyPhilosophyNatural product bioactivities and synthesisPharmacological Effects of Natural CompoundsPlant biochemistry and biosynthesis
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