Downregulated IRF8 in Monocytes and Macrophages of Patients with Systemic Sclerosis May Aggravate the Fibrotic Phenotype
Yasushi Ototake, Yukie Yamaguchi, Miho Asami, Noriko Komitsu, Asami Akita, Tomoya Watanabe, Miwa Kanaoka, Daisuke Kurotaki, Tomohiko Tamura, Michiko Aihara
Topics & Concepts
MonocyteImmunologyMacrophageFibrosisPathogenesisIRF8BiologyMedicinePathologyGene expressionIn vitroGeneBiochemistrySystemic Sclerosis and Related DiseasesDermatologic Treatments and ResearchMast cells and histamine