Effects of omega-3, omega-6, and total dietary polyunsaturated fatty acid supplementation in patients with atherosclerotic cardiovascular disease: a systematic review and meta-analysis
Siqi Luo, Hongmei Hou, Yongjin Wang, Yun Li, Le Zhang, Hui Zhang, Qingzhe Jin, Gangcheng Wu, Xingguo Wang
Abstract
: omega-3 intake is associated with a reduced risk of all-cause mortality, CVD mortality, and CVD events in ASCVD patients, while omega-6 or total PUFA intake showed no significant association. Increasing the omega-3 intake by 1 g per d resulted in a 3.5% decrease in the risk of death. These findings support the recommendation of supplements with omega-3 fatty acids for the secondary prevention of ASCVD.
Topics & Concepts
Meta-analysisPolyunsaturated fatty acidMedicineRandomized controlled trialOmegaDiseaseInternal medicineOmega 3 fatty acidProspective cohort studyFatty acidDocosahexaenoic acidBiologyBiochemistryPhysicsQuantum mechanicsFatty Acid Research and HealthCholesterol and Lipid MetabolismNutritional Studies and Diet