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3-Arylsulfonylquinolines from <i>N</i>-Propargylamines via Cascaded Oxidative Sulfonylation Using DABSO

Ashis Mathuri, Milan Pramanik, Prasenjit Mal

2022The Journal of Organic Chemistry20 citationsDOI

Abstract

We report a cascaded oxidative sulfonylation of N-propargylamine via a three-component coupling reaction using DABCO·(SO2)2 (DABSO). 3-Arylsulfonylquinolines were obtained by mixing diazonium tetrafluoroborate, N-propargylamine, and DABSO under argon atmosphere in dichloroethane (DCE) for 1 h. In a radical pathway, DABSO was utilized as the sulfone source and an oxidant in this radical-mediated cascaded reaction.

Topics & Concepts

ChemistryDABCOOxidative coupling of methaneSulfoneOxidative phosphorylationTetrafluoroborateDichloroethanePhotochemistryMedicinal chemistryOrganic chemistryPolymer chemistryOctaneCatalysisIonic liquidBiochemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions
3-Arylsulfonylquinolines from <i>N</i>-Propargylamines via Cascaded Oxidative Sulfonylation Using DABSO | Litcius