Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography
Chase E. Herman, Lie Min, Leila H. Choe, Ronald W. Maurer, Xuankuo Xu, Sanchayita Ghose, Kelvin H. Lee, Abraham M. Lenhoff
Topics & Concepts
ChemistryChromatographyElutionMonoclonal antibodySize-exclusion chromatographyProtein aggregationIon chromatographyPolishingAffinity chromatographyFraction (chemistry)AntibodyEnzymeBiochemistryImmunologyComposite materialMaterials scienceBiologyProtein purification and stabilityMonoclonal and Polyclonal Antibodies ResearchViral Infectious Diseases and Gene Expression in Insects