<i>In Vitro</i> Activity of Nitroxoline in Antifungal-Resistant <i>Candida</i> Species Isolated from the Urinary Tract
Frieder Fuchs, Alexander Maximilian Aldejohann, A Hoffmann, Grit Walther, Oliver Kurzai, Axel Hamprecht
Abstract
Infections by drug-resistant fungi are increasingly reported worldwide; however, only few novel antifungals are being developed. The old antimicrobial nitroxoline is currently repurposed for oral treatment of bacterial urinary tract infections (UTI).
Topics & Concepts
Broth microdilutionFluconazoleMicrobiologyAntimicrobialAmphotericin BAnidulafunginUrinary systemMinimum inhibitory concentrationMedicineAgarAntifungalBiologyBacteriaInternal medicineMicafunginGeneticsAntifungal resistance and susceptibilityUrinary Tract Infections ManagementPhenothiazines and Benzothiazines Synthesis and Activities