Rational structural design of aromatic Azo photoactive small molecules for biomedical applications
Junjie Ding, Ze Huang, Duoteng Zhang, Yunwei Qu, Shiji Zhang, Congcong Zhang, Bin Fang, Lin Li, Wei Huang
Abstract
heteroaryl Azo derivatives, and highlight the latest biomedical application advances, including biological imaging and detection, drug delivery, photopharmacology, phototherapy, miscellanea photo responsive biomaterials and constructs, and control in chemical biology. Furthermore, we discuss clinical translation challenges and opportunities in this field, proposing innovative strategies to address critical issues. This review aims to substantially advance the burgeoning field of aromatic Azo photoactive small molecules for biomedical applications.
Topics & Concepts
Small moleculeNanotechnologyRational designIsomerizationSubstituentChemistryPhotoisomerizationMoleculeCombinatorial chemistryMolecular engineeringMaterials scienceAromaticityAzobenzeneTranslation (biology)Context (archaeology)Photochromic and Fluorescence ChemistryNanoplatforms for cancer theranosticsLuminescence and Fluorescent Materials