A nitric oxide responsive AIE probe for detecting the progression of osteoarthritis
Jin Pan, Guojie Xu, Xichi Chen, Shicheng Li, Lin Cheng, Ping Sui, Jiaqi Ye, Xuerui Yang, Shanshan Xi, Fabiao Yu, Tongmeng Jiang
Abstract
An AIE probe was established for reacting with NO and emitting fluorescence in arthritic joints/chondrocytes. This AIE probe is appropriate for detecting the progression of osteoarthritis.
Topics & Concepts
Nitric oxideFluorescenceIn vivoOsteoarthritisIn vitroEthylene glycolAggregation-induced emissionBenzotriazoleEthylene oxidePEG ratioChemistryMaterials scienceBiophysicsMedicineBiochemistryPolymerOrganic chemistryBiologyPathologyOpticsBiotechnologyEconomicsAlternative medicinePhysicsFinanceCopolymerInflammatory mediators and NSAID effectsLuminescence and Fluorescent MaterialsMolecular Sensors and Ion Detection