TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer
Liancheng Fan, Yiming Gong, Yuman He, Wei‐Qiang Gao, Xuesen Dong, Baijun Dong, Helen He Zhu, Wei Xue
Topics & Concepts
BiologyAndrogen receptorTranscription factorCancer researchProstate cancerDownregulation and upregulationEpigeneticsSOX2Neuroendocrine differentiationChromoplexyGeneCancerGeneticsPCA3Prostate Cancer Treatment and ResearchUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease