Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT
Can Li, Yuying Zhu, Weiwei Liu, Wendie Xiang, Sijun He, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima
Topics & Concepts
HaCaTMitophagyParkinPINK1MitochondrionCell biologyApoptosisGene silencingMolecular biologyBiologyProgrammed cell deathChemistryAutophagyBiochemistryMedicineIn vitroParkinson's diseasePathologyGeneDiseaseinterferon and immune responsesUbiquitin and proteasome pathwaysNF-κB Signaling Pathways