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Thermodynamic and kinetic hydricity of transition metal hydrides

Kelsey R. Brereton, Nicholas E. Smith, Nilay Hazari, Alexander J. M. Miller

2020Chemical Society Reviews107 citationsDOIOpen Access PDF

Abstract

, as determined through equilibrium measurements and thermochemical cycles. Kinetic hydricity represents the rate of hydride transfer from one species to another, as measured through kinetic analysis. This tutorial review describes the common methods for experimental and computational determination of thermodynamic and kinetic hydricity, including advice on best practices and precautions to help avoid pitfalls. The influence of solvation on hydricity is emphasized, including opportunities and challenges arising from comparisons across several different solvents. Connections between thermodynamic and kinetic hydricity are discussed, and opportunities for utilizing these connections to rationally improve catalytic processes involving hydride transfer are highlighted.

Topics & Concepts

HydrideHeterolysisChemistryCatalysisKinetic energySolvationThermodynamicsTransition metalReactivity (psychology)Physical chemistryMetalComputational chemistryOrganic chemistryMoleculePhysicsQuantum mechanicsAlternative medicineMedicinePathologyAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisOrganometallic Complex Synthesis and Catalysis
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