Limosilactobacillus fermentum Limits Candida glabrata Growth by Ergosterol Depletion
Isabella Zangl, Reinhard Beyer, Arianna Gattesco, Román Labuda, Ildiko-Julia Pap, Joseph Strauss, Christoph Schüller
Abstract
The yeast Candida glabrata , an opportunistic fungal pathogen, and the bacterium Limosilactobacillus fermentum both inhabit the human gastrointestinal and vaginal tract. Lactobacillus species, belonging to the healthy human microbiome, are thought to prevent C. glabrata infections. We investigated the antifungal effect of Limosilactobacillus fermentum on C. glabrata strains quantitively in vitro .
Topics & Concepts
Candida glabrataLactobacillus fermentumErgosterolMicrobiologyBiologyYeastMicrobiomePathogenBiofilmGastrointestinal tractAntifungalBacteriaBotanyBiochemistryLactobacillus plantarumLactic acidBioinformaticsGeneticsProbiotics and Fermented FoodsGut microbiota and healthMicrobial Metabolites in Food Biotechnology