Enantioselective [3 + 2] annulation of tryptanthrin-derived ketimines and 2-naphthols: access to polycyclic indolo[2,1-<i>b</i>]quinazoline derivatives
Yong You, Guo-Ying Gan, Qun Li, Xiong‐Li Liu, Yanping Zhang, Zhen‐Hua Wang, Jian‐Qiang Zhao, Wei‐Cheng Yuan
Abstract
An efficient method has been disclosed for the highly enantioselective synthesis of optically pure heptacyclic dihydronaphthofuran-fused indolo[2,1- b ]quinazoline derivatives.
Topics & Concepts
Enantioselective synthesisChemistryAnnulationQuinazolineOrganic chemistryCombinatorial chemistryStereochemistryCatalysisAxial and Atropisomeric Chirality SynthesisQuinazolinone synthesis and applicationsAdvanced Synthetic Organic Chemistry