Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies
Jackson Weako, Abdullahi İbrahim Uba, Özlem Keskin, Attila Gürsoy, Kemal Yelekçi
Topics & Concepts
FumagillinChemistryMethionineBiochemistryVirtual screeningComputational biologyStereochemistryBiologyDrug discoveryCancer researchAmino acidAngiogenesisPeptidase Inhibition and AnalysisNeuropeptides and Animal PhysiologyChemical Synthesis and Analysis