Receptor‐like kinase cleavage: molecular mechanism and regulatory functions in plants
Meng Yu, Xiaotong Nie, Shaoying Ke, Li Li, Bin Li
Abstract
Receptor-like kinases (RLKs) are essential in nearly all plant life activities. To date, most RLK research focuses on their plasma membrane functions as holoreceptors. This review introduces a distinct mechanism: RLK cleavage-regulated signal transduction in plants. We summarize cleavable RLKs and describe their cleavage forms, focusing on molecular mechanisms and functions for plant development and plant-microbe interactions. Notably, we emphasize that the released intracellular domain of RLKs translocates to the nucleus, mediating noncanonical signaling pathways. This review provides valuable insights into plant biology and underscores the significance of RLK cleavage in plant signaling.
Topics & Concepts
Cleavage (geology)BiologyCell biologySignal transductionKinaseMechanism (biology)IntracellularReceptorProtein kinase domainBotanyGeneBiochemistryPhysicsQuantum mechanicsPaleontologyFracture (geology)MutantPlant Reproductive BiologyLegume Nitrogen Fixing SymbiosisPlant Parasitism and Resistance