Defect-engineered porphyrinic metal–organic framework nanoparticles for targeted multimodal cancer phototheranostics
Chenyuan Wang, Chuxiao Xiong, Zhike Li, Liefeng Hu, Jianshuang Wei, Jian Tian
Abstract
Defect-engineered porphyrinic MOF nanoparticles were fabricated with an in situ one-pot protocol using cypate as the co-ligand and modulator. This multifunctional nanoplatform integrated the photothermal and multimodal imaging properties of cypate with the photodynamic effects of porphyrins, thus achieving targeted multimodal cancer phototheranostics after folic acid modification.
Topics & Concepts
NanoparticleNanotechnologyMetal-organic frameworkLigand (biochemistry)Materials scienceCancerChemistryMedicineOrganic chemistryReceptorAdsorptionInternal medicineBiochemistryNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and ApplicationsAdvanced Nanomaterials in Catalysis