Photoredox-catalyzed regio- & stereoselective C(sp<sup>2</sup>)–H cyanoalkylation of enamides with cycloketone oximes <i>via</i> selective C–C bond cleavage/radical addition cascade
Ting Guan, Jingyu Guo, Qinghong Zhang, Xin-Wen Xu, Xiaoyu Yu, Yu Zhang, Kai Zhao
Abstract
A visible-light-induced regio- and stereoselective C(sp 2 )–H coupling reaction of enamides with cycloketone oximes is developed under mild and environmentally-friendly conditions.
Topics & Concepts
StereoselectivityChemistryCatalysisBond cleavageCascadeCleavage (geology)StereochemistryMedicinal chemistryRegioselectivityOrganic chemistryFracture (geology)EngineeringChromatographyGeotechnical engineeringCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesRadical Photochemical Reactions