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Immune thrombocytopenia (<scp>ITP</scp>) in pregnancy

James B. Bussel, Katherine A. Knightly

2024British Journal of Haematology15 citationsDOIOpen Access PDF

Abstract

Immune thrombocytopenia (ITP) in pregnancy is challenging for both mother and fetus. Understanding the pathophysiology, treatments, and risks to the mother and fetus leads to proper management resulting in successful pregnancy and delivery in almost all cases. 1 ITP in a pregnant woman has many similarities to ITP not in pregnancy although gestational thrombocytopenia can be confused with ITP. However, recognizing differences is instrumental in avoiding bleeding complications and toxicities of treatment. This Nutshell review focuses on the natural history of ITP in pregnancy, its treatment, and dilemmas.

Topics & Concepts

PregnancyImmune thrombocytopeniaMedicineFetusNatural historyImmune systemPathophysiologyGestationObstetricsPediatricsImmunologyPlateletInternal medicineGeneticsBiologyPlatelet Disorders and TreatmentsBlood groups and transfusionBlood properties and coagulation