Morphine may act via DDX49 to inhibit hepatocellular carcinoma cell growth
Huijun Dai, Jifeng Feng, Zhenhua Nan, Lijuan Wei, Fei Lin, Ren Jie Jin, Suisui Zhang, Xiaoxia Wang, Linghui Pan
Abstract
. Morphine decreases DDX49 expression in HCC cells. Our results suggest that DDX49 contributes to HCC, and that morphine may exert anti-cancer effects by down-regulating it.
Topics & Concepts
Hepatocellular carcinomaMorphineCancer researchMedicinePharmacologyInternal medicineCancer, Stress, Anesthesia, and Immune ResponseNeuropeptides and Animal PhysiologyPharmacological Receptor Mechanisms and Effects