A rank-based approach to improve the efficiency of inferential seamless phase 2/3 clinical trials with dose optimization
Xin Wang, Min Chen, Shuyu Chu, Rong Fan, Ivan S. F. Chan
Topics & Concepts
MedicineType I and type II errorsSelection (genetic algorithm)CorrelationStatisticsRank (graph theory)Phase (matter)BiomarkerMathematicsComputer scienceMachine learningOrganic chemistryGeometryBiochemistryCombinatoricsChemistryStatistical Methods in Clinical TrialsOptimal Experimental Design MethodsComputational Drug Discovery Methods