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Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy

Magda F. Mohamed, Amna A. Saddiq, Ismail A. Abdelhamid

2020Bioorganic Chemistry16 citationsDOI

Topics & Concepts

ChemistryApoptosisCytochrome cCytotoxic T cellMoietyFlow cytometryCaspaseCell cultureIC50Intrinsic apoptosisColorectal cancerIn vitroCancer cellMolecular biologyStereochemistryBiochemistryCancerProgrammed cell deathBiologyGeneticsSynthesis and biological activitySynthesis and Biological ActivityQuinazolinone synthesis and applications
Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy | Litcius