Litcius/Paper detail

Recent Advances in the Fixation of CO<sub>2</sub> to Form N‐Containing Heterocyclic Compounds

Qi Zhang, Xin Jin

2025Chemistry - A European Journal9 citationsDOI

Abstract

Abstract N‐containing heterocyclic compounds are common chemical structures in drugs, bioactive compounds, and natural products. Using CO 2 as a C1 source for synthesizing N‐containing heterocyclic compounds aligns with the concepts of green chemistry and sustainability. In recent years, the synthesis of N‐containing heterocyclic compounds has been extensively and intensively studied. However, significant challenges remain, such as thermodynamic limitations, low catalytic efficiency, and harsh reaction conditions. Catalysts play an essential role in the catalytic activation of CO 2 and/or substrates, thereby facilitating CO 2 conversion. This review provides an overview of several typical N‐containing heterocyclic compounds converted from CO 2 , such as oxazolidinones, quinazoline‐2,4(1 H ,3 H )‐diones, benzimidazoles, and benzimidazolones. The most recent catalysts used in these reactions are discussed, emphasizing their mechanistic roles in the reaction process.

Topics & Concepts

CatalysisChemistryCombinatorial chemistryOrganic chemistryGreen chemistryCarbon fixationReaction mechanismCarbon dioxideCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and CatalysisQuinazolinone synthesis and applications