SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation
Wenxin Zhang, Junren Dai, Guixue Hou, Hao Liu, Shanliang Zheng, Xingwen Wang, Qingyu Lin, Yi Zhang, Minqiao Lu, Yafan Gong, Zhiyuan Xiang, Yan Yu, Ying Hu
Topics & Concepts
GPX4GSTP1BiologyGlutathioneDownregulation and upregulationCell biologyCancer researchCancer cellGlutathione peroxidaseCancerBiochemistryEnzymeGeneticsGeneFerroptosis and cancer prognosisEpigenetics and DNA MethylationGlutathione Transferases and Polymorphisms