The role of gut microbiota in patients with benign and malignant brain tumors: a pilot study
Haixiao Jiang, Wei Zeng, Xiaoli Zhang, Yunlong Pei, Hengzhu Zhang, Yuping Li
Abstract
was established. Diagnostic models confirmed that this panel could distinguish between brain tumor patients and healthy patients. Additionally, gut microbiota can affect the differentiation and proliferation of brain tumors via several metabolic pathways based on annotations from the Kyoto Encyclopedia of Genes and Genomes (KEGG). This is the first study designed to investigate whether gut microbiota differs between benign and malignant brain tumor patients, and our work concluded that intestinal flora is a valuable tool for the diagnosis and treatment of brain tumors.
Topics & Concepts
Gut floraAkkermansiaGliomaBrain tumorAkkermansia muciniphilaFusobacteriumPathologyBiologyMeningiomaBifidobacteriumBiomarkerMedicineImmunologyCancer researchBacteriaBacteroidesLactobacillusBiochemistryGeneticsGut microbiota and healthAdvanced Neuroimaging Techniques and ApplicationsDiet and metabolism studies