Discovery of semisynthetic celastrol derivatives exhibiting potent anti-ovarian cancer stem cell activity and STAT3 inhibition
Na Li, Chaobo Li, Juan Zhang, Qian Jiang, Zhaoxue Wang, Shao‐Zhen Nie, Zhenzhen Gao, Guangyao Li, Hao Fang, Shaoda Ren, Xiaojing Li
Topics & Concepts
CelastrolStem cellOvarian cancerChemistryCancer researchCancer stem cellSTAT3PharmacologyCancerBiochemistryMedicineApoptosisBiologyCell biologyInternal medicineNatural Compounds in Disease TreatmentBioactive Compounds and Antitumor AgentsNatural product bioactivities and synthesis