Grafting of Gd-DTPA onto MOF-808 to enhance MRI performance for guiding photothermal therapy
Mingjie Jia, Xinyu Yang, Yanan Chen, Meie He, Weixiu Zhou, Jiao‐Min Lin, Lu An, Shiping Yang
Abstract
A MRI guided photothermal therapy agent Gd-DTPA-MOF-808@PANI was developed through grafting T 1 -weight contrast agent Gd-DTPA molecule within the porous channel of MOF-808 and modified with polyaniline (PANI).
Topics & Concepts
Photothermal therapyMaterials scienceMagnetic resonance imagingGadoliniumChelationNanoparticleRelaxation (psychology)Biomedical engineeringNuclear magnetic resonanceNanotechnologyRadiologySocial psychologyMedicineMetallurgyPhysicsPsychologyNanoplatforms for cancer theranosticsLanthanide and Transition Metal ComplexesNanoparticle-Based Drug Delivery