Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase
Busra Ozturk Aydin, Derya Aktaş Anıl, Yeliz Demir, Mehmet Abdullah Alagöz
Topics & Concepts
Carbonic anhydraseChalconeAcetylcholinesteraseChemistryAchéEnzymeActive siteStereochemistryThiadiazolesBiochemistryOrganic chemistryCholinesterase and Neurodegenerative DiseasesEnzyme function and inhibitionSynthesis and biological activity