Identification of Antifungal Compounds against Multidrug-Resistant Candida auris Utilizing a High-Throughput Drug-Repurposing Screen
Yu‐Shan Cheng, José Santinni Roma, Min Shen, Caroline Mota Fernandes, Patricia Tsang, Harriet Forbes, Helena I. Boshoff, C. Lazzarini, Maurizio Del Poeta, Wei Zheng, Peter R. Williamson
Abstract
Candida auris is an emerging fatal fungal infection that has resulted in several outbreaks in hospitals and care facilities. Current treatment options are limited by the development of drug resistance.
Topics & Concepts
Candida aurisMultiple drug resistanceDrug repositioningFluconazoleDrug resistanceAntifungalAntifungal drugsMicrobiologyBiologyAntifungal drugDrugAmphotericin BMulti drug resistantMedicinePharmacologyAntifungal resistance and susceptibilityFungal Infections and StudiesMicrobial Natural Products and Biosynthesis