Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host Interactome
Jiansong Fang, Qihui Wu, Fei Ye, Chuipu Cai, Lvjie Xu, Yong Gu, Qi Wang, Ailin Liu, Wenjie Tan, Guanhua Du
Abstract
identification of drug candidates on COVID-19, which may facilitate the discovery of antiviral drug therapies.
Topics & Concepts
InteractomeIn silicoComputational biologyIdentification (biology)Host (biology)Sars virusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)VirusBiologyVirologyMedicineGeneticsGeneInfectious disease (medical specialty)DiseasePathologyBotanyComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchSynthesis and biological activity