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Design, synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives as selective COX-2 inhibitors

Ahmed S. Ismael, Noha H. Amin, Mohammed T. El‐Saadi, Mohammed R.A. Ali, Hamdy M. Abdel‐Rahman

2021Journal of Molecular Structure25 citationsDOI

Topics & Concepts

ChemistryCelecoxibIn vivoPyrazolineED50IsozymeEdemaCyclooxygenasePharmacologyAnti-inflammatoryPyridineIC50StereochemistrySelectivityEnzymeBiochemistryIn vitroOrganic chemistryCatalysisPsychiatryBiotechnologyBiologyPsychologyMedicineInflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis of β-Lactam Compounds
Design, synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives as selective COX-2 inhibitors | Litcius