A polysaccharide deacetylase enhances bacterial adhesion in high-ionic-strength environments

Abstract

. In this work, we show that the holdfast polysaccharide deacetylase HfsH plays an important role in adherence in high-ionic-strength environments. We show that increasing expression of HfsH improves holdfast binding in high-ionic-strength environments. We conclude that HfsH plays a role in modulating holdfast binding at high ionic strength and hypothesize that this modulation occurs through varied deacetylation of holdfast polysaccharides.

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