Advance in the Synthesis of Sulfoxides and Sulfinamides from β-Sulfinyl Esters
Xianjie Yin, Qiaoling Zhang, Qingle Zeng
Abstract
Sulfoxides and sulfinamides play important roles in the pharmaceutical industry, organic synthesis and fine chemicals. This review will demonstrate that, under catalysis by transition metals, β-sulfinyl esters, as nucleophilic reagents, react with a variety of electrophilic reagents to produce sulfoxides and sulfinamides. The important prospect of the asymmetric catalytic synthesis of chiral sulfur-containing molecules in this field is described.
Topics & Concepts
ChemistryReagentNucleophileElectrophileCatalysisEnantioselective synthesisOrganic synthesisCombinatorial chemistrySulfurOrganic chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsSynthesis and Catalytic Reactions